High pressure homogenizers are widely used, for multiple Applications, in the pharmaceutical, cosmetics, nutraceuticals and chemical industries to make emulsions, suspensions and dispersions.
Our class-leading, fully featured systems are versatile, user-friendly and are used globally for the application types below.
高压均质机可以广泛使用,具有多种应用在制药、化妆品、营养保健食品和化学工业,以制造微乳剂、悬浮剂和分散剂。
我们出色先进、功能齐全的系统是全能、友好和全球供应,其应用类型如下:
Producing the smallest, most uniform particle sizes in emulsions and dispersions in the fewest passes, improving product stability.
以最少的均质次数生产粒径最小、最均一的乳剂和分散剂,增加产品的稳定性。
The quality parameters of emulsions, suspensions and dispersions are:
乳剂、分散剂和悬浮剂的质量指标为:
Smallest droplet size – smallest ratio of droplet surface area to droplet volume.
最小的液滴-液滴表面积和液滴体积的比率最小。
Narrow particle size distribution – most of the droplets at or below the target size and no "tails" on the distribution graph.
非常窄的粒径分布-大多数的液滴处在或小于靶标尺寸并且没有“拖尾”现象在分布曲线图里。
Our homogenizer's excel at efficiently producing emulsions, suspensions and dispersions with droplets and particles in the size range from a few nanometers to a few micrometers and very narrow particle size distributions. This is accomplished by three different physical mechanisms:
我们的高压均质机胜任于高效生产处理带液滴的乳剂、分散剂和悬浮剂,处理后的粒径范围从非常小的纳米到微米级别且粒径分布非常窄。经由三个不同的物理机制完成:
1.Impingement on entry to the nozzle area.
撞击进入喷嘴区。
2.High liquid shear in the nozzle.
高速液体剪切在喷嘴。
3.Sudden pressure drop upon discharge.
卸压时的瞬间压降。
Our Homogenizers - more benefits:
我们均质机-更多益处:
Production of uniform target nanoparticle sizes in the fewest passes.
以最少的均质次数生产均一尺寸的靶标纳米颗粒。
Higher stability (longer shelf life).
更高的稳定性(更长的保质期)。
Sterilisation by filtration (for medical suspensions).
医用悬浮剂的过滤灭菌。
Higher efficacy (absorption), controlled release, odour and flavour masking.
更高的吸收效率、控制缓释、气味和风味的掩盖。
The benefits above, and others, often lead to lower production costs. Our on-going maintenance costs are also some of lowest in the industry.
以上的益处,和其它的优势所带来更低的生产成本。我们后继的维护费用也是工业里最低的。
Our Homogenizers - more features:
我们均质机的更多特点
The following unique features enable the user to create emulsions and dispersions with smallest particles sizes and narrowest particle size distributions in the smallest number of passes:
以下的独特特征可使用户以最少的均质次数制造最小粒径和最窄粒径分布的乳剂和悬浮剂:
High, Very High and Ultra High Pressure Homogenizers, to maximise the intensity of the process.
高压、非常高压和超高压均质机,以最大限度的提高处理过程的强度。
Exceptionally wide range of pressure, for maximum versatility.
非常广泛的压力范围,可获得最大的通用性。
Precise control of the pressure throughout the range, and constant pressure once set, for narrowest particle size distribution, reproducibility and scalability.
精确控制量程内的压力,设定后即可保持恒定压力,可获得最窄粒径分布,具有优良的重现性和可扩展性。
Sophisticated temperature control systems, including pre- and post-cooling or heating, to preserve product integrity.
精密的温度控制系统,包括预冷和出料冷却或加热,以保持产品的完整性。
The table below illustrates.
下表说明产品和建议的压力范围-以MPa和psi为单位
Products and Pressure Ranges - in MPa and psi
Liposomes脂质体 20 to 150 MPa --> 3000 to 22,000 psi
Encapsulation包封 20 to 150 MPa --> 3000 to 22,000 psi
Microemulsions微乳 20 to 200 MPa --> 3000 to 30,000 psi
Deagglomeration松团作用 20 to 350 MPa --> 3000 to 50,000 psi
Nanosuspensions纳米悬乳剂 20 to 400 MPa --> 3000 to 60,000 psi
Polysaccharides多糖
Nano Cellulose纳米纤维素
(1)Preheating to 80°C (lipid melt temperature) is possible.
可预热到80°C (脂质融化温度)
Cell Rupture, Disruption, Lysis are methods for disrupting cell walls and cell membranes to release biological molecules, whilst maintaining intracellular contents integrity.
细胞破裂、破碎、溶解是细胞壁和细胞膜破碎以释放生物分子,同时保留细胞内含物完整的方法。
Cell Disruption / Lysis细胞破碎/裂解
The apparatus used for cell disruption is often referred to as a 'French pressure cell press', or 'French Press'. Our 'Stansted' range of 'Benchtop' Cell Disruptors provide an industry-leading, powerful and extremely user friendly replacement for the French ® pressure cell system with capabilities for batch and continuous operation.
用于细胞破碎的仪器常会被联想到'French pressure cell press'或者 'French Press'。我们的“'Stansted' 系列 'Benchtop'细胞破碎仪提供业界领先、强大和极为用户友好的French ®类型高压细胞系统,具有单批次和连续运行的功能。
Our very high pressure performance up to 58,000 psi (4,000 bar) ensure our systems can handle the toughest cells while a versatile range of flexible lysing valves ensure finely controlled operation even when working the softest.
我们非常高压力性能达58,000 psi (4000bar)保证我们的系统可以处理最坚硬的细胞,同时多功能范围的灵活的溶解阀保证非常好的控制处理最柔软的样品。
Common Applications include共同的应用包括:
E.coli大肠杆菌
Yeasts (s cerivises, Pichia)酵母菌
Algae藻类
Mamalllian cells马马利亚血细胞
Bacillus 杆菌
Staph a.葡萄杆菌
CBD / Cannabinoids大麻素类
... and many others
Enzyme preparation, Cell extract preparation Bacterial and plant tissue disintegration Recovery of intercellular proteins and nucleic acid. Preparation of viral antigens, membrane preparation for phizobia and pseudomonads ...... etc.)
生物细胞破壁: (大肠杆菌、酵母菌、霉菌......等等) 酶的分离和隔离,细菌和植物组织断裂,细胞内蛋白质和核酸的回收,制备EIA测试包的病毒性抗原,phizobia和假单体的膜制备,胚芽和毒素的回收,蛋白质纯化,细胞提取制备等 范围包括:微生物(大肠杆菌、酵母菌、酶菌)、藻类、动物细胞和组织、植物细胞和组织、昆虫、病毒、环境样品等。
Our scalable technology offer practical processing from 1ml, through bench top, pilot and production systems with flow rate in excess of 1000 l/hr.
我们的可扩展技术提供实际处理从1ml,实验桌面型,中试和生产系统流量超过1000升每小时。